产品货号:
Z29412
中文名称:
VPS53抗体
英文名称:
Anti-VPS53 Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-VPS53 Antibody |
指标别名 | HCCS1;hVps53L;pp13624;VPS53 |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | ELISA,WB,ICC,IF |
基因名称 | VPS53 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | VPS53 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human VPS53.The immunogen is located within the last 50 amino acids of VPS53. |
计算分子量 | 80kDa |
成分 | VPS53 Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | VPS53 Antibody is affinity chromatography purified via peptide column. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes.The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits:VPS52,VPS53,and VPS54.Depletion of any of these three proteins,such as by RNAi,impairs the retrograde transport of multiple TGN proteins.VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell,suggesting that VPS53 may be an important drug target in HIV treatment.At least five isoforms of VPS53 are known to exist. |
Uniprot ID | Q5VIR6 |
基因名全称 | Vacuolar protein sorting 53 homolog (S.cerevisiae) |
蛋白名全称 | Vacuolar protein sorting 53 homolog (S.cerevisiae) |
推荐稀释比 | VPS53 antibody can be used for detection of VPS53 by Western blot at 0.5 ~ 1μg/mL.Antibody can also be used for immunocytochemistry starting at 5μg/mL.For immunofluorescence start at 2.5μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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